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16.04.2012 10:00
Women undergoing treatment for breast cancer might fight off distressing side effects and improve psychological well-being by staying off the couch. According to the University of Miami (UM) study, women who are physically active during treatment have less depression and an enhanced quality of life and report less debilitating fatigue...
When women at high risk of breast cancer viewed a customized web-based decision guide about prevention options, they were more likely to make a choice about prevention and to feel comfortable with their choice, a new study finds...
15.04.2012 10:00
Researchers at the Hospital de Mar Research Institute (IMIM) have discovered that the protein LOXL2 has a function within the cell nucleus thus far unknown. They have also described a new chemical reaction of this protein on histone H3 that would be involved in gene silencing, one of which would be involved in the progression of breast, larynx, lung and skin tumours...
14.04.2012 10:00
Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK. The researchers found a family of proteins to be twice as prevalent in clinical samples obtained from breast cancer patients who were resistant to chemotherapy than those who were successfully treated...
13.04.2012 11:00
Women undergoing treatment for breast cancer can experience cognitive declines, such as decreased verbal fluency or loss of memory and attention. Often experienced by patients undergoing chemotherapy, the declines have become known as "chemo brain." However, a health psychologist at the University of Missouri says "chemo brain" isn't always to blame...
12.04.2012 11:00
A new supplement in the journal Cancer outlines an innovative model to address a wide range of physical issues faced by women with breast cancer and offers hope for improved function and full participation in life activities for patients through rehabilitation and exercise...
12.04.2012 00:00
Breast cancer is the most commonly diagnosed cancer in the UK, with almost 48,000 women and about 300 men diagnosed every year. About one in eight women in the UK will develop breast cancer at some stage during their life, but thanks to better awareness, treatments and screening, more women than ever are surviving breast cancer in the UK...
11.04.2012 12:00
More than 60 percent of breast cancer survivors report at least one treatment-related complication even six years after their diagnosis, according to a new study led by a researcher from the Perelman School of Medicine at the University of Pennsylvania...
10.04.2012 11:00
One in eight women will be diagnosed with breast cancer during her lifetime. The earlier cancer is detected, the better the chance of successful treatment and long-term survival. However, early cancer diagnosis is still challenging as testing by mammography remains cumbersome, costly, and in many cases, cancer can only be detected at an advanced stage. A team based in the Dept...
False-positive mammograms could be an indicator of underlying pathology that could result in breast cancer, according to a study published in the Journal of the National Cancer Institute...
Women with ductal carcinoma in situ (DCIS) have high rates of diagnostic and invasive breast procedures after treatment with breast-conserving surgery (BCS) according to a study published in the Journal of the National Cancer Institute...
10.04.2012 10:00
The first large-scale U.S.-based study to evaluate the link between an injectable form of progestin-only birth control and breast cancer risk in young women has found that recent use of a year or more doubles the risk. The results of the study, led by breast cancer epidemiologist Christopher I. Li, M.D., Ph.D...
09.04.2012 19:00
Chinese women who ate plenty of cabbage, broccoli, cauliflower - cruciferous vegetables - were found to have better breast cancer survival rates compared to other breast cancer patients, researchers explained at the AACR (American Association for Cancer Research) Annual Meeting 2012, Chicago, USA. Sarah J. Nechuta, M.P.H., Ph.D...
09.04.2012 10:00
Inflammatory breast cancer (IBC) is a very aggressive, often misunderstood type of cancer that is diagnosed more frequently in younger women compared with other types of breast cancer. The five-year survival rate is between 25 and 50 percent - significantly lower than the survival rate for other types of breast cancer...
An international team of scientists, including four at Simon Fraser University, has made a discovery that will change the way the most deadly form of breast cancer is treated. The journal Nature has just published the team's findings online in the paper The clonal and mutational evolution spectrum of primary triple negative breast cancers...
American women of African ancestry are more likely than European Americans to have estrogen receptor (ER) negative breast cancer. There continues to be discussion about the role of low levels of vitamin D in the development of breast cancer for these women...
07.04.2012 10:00
Removing a lipoprotein receptor known as SR-BI may help protect against breast cancer, as suggested by new findings presented at the American Association for Cancer Research Annual Meeting 2012 by Jefferson's Kimmel Cancer Center researchers. In vitro and mouse studies revealed that depletion of the SR-BI resulted in a decrease in breast cancer cell growth...
05.04.2012 15:00
A study published in the April 4 issue of JAMA reveals that ultrasound screening or magnetic resonance imaging (MRI) in addition to annual mammography increases breast cancer detection rates among women with an increased risk of breast cancer and dense breast tissue...
05.04.2012 11:00
Studies exploring the relationship between soy consumption and breast cancer have been mixed, but new research introduces a new thought: Could women with breast cancer who began eating soy as an adult develop a tumor more resistant to treatment? That's the suggestion of a new study in animal models that could provide important hints for women with breast cancer who eat soy...
05.04.2012 10:00
Eating cruciferous vegetables after breast cancer diagnosis was associated with improved survival among Chinese women, according to results presented at the AACR Annual Meeting 2012, held March 31 - April 4...
04.04.2012 23:00
Females at risk of breast cancer or dense breast tissue benefit from having additional MRI or ultrasound screening when undergoing their annual mammography, researchers reported in JAMA (Journal of the American Medical Association) this week. The authors explained that the additional screening improves breast cancer detection rates...
04.04.2012 10:00
1. Mammography Screening Leads to Overdiagnosis of Breast Cancer Women undergo mammography screening to detect cancer in its early stages. Theoretically, early detection saves lives. However, newer research is questioning whether finding cancer early is better. Researchers in Norway sought to determine the percentage of overdiagnosis of breast cancer attributable to mammography screening...
A new class of agents known as c-Src inhibitors is being tested in a number of different ways to treat breast cancer, but researchers at Georgetown Lombardi Comprehensive Cancer Center caution that they should not be used in combination with estrogen to treat endocrine resistant breast cancer...
At the time of diagnosis, the majority of breast cancers are categorized as estrogen-receptor positive, or hormone sensitive, which means their cancerous cells may need estrogen to grow. Patients with this type of cancer often respond favorably to treatments called aromatase inhibitors, like tamoxifen, which cause cell death by preventing estrogen from reaching the cancerous cells...
03.04.2012 18:00
The "should we shouldn't we" debate continues in regards to routine breast cancer screening, with new research from Harvard School of Public Health (HSPH), indicating that between 15% and 25% of cases are overdiagnosed. Routine mammograms have become the norm since the late 1980s, and have been thought to be the frontline in the fight against breast cancer...
03.04.2012 11:00
When a mother undergoes genetic testing to determine whether she carries a gene for hereditary breast cancer, the parents must then decide whether and how to share this risk information with their children...
03.04.2012 10:00
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR Annual Meeting 2012...
02.04.2012 10:00
A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer metastasis and identifies new therapeutic targets for a lethal form of invasive breast cancer that is notoriously resistant to treatment...
31.03.2012 10:00
An international team of researchers led by the University of Melbourne has used new technology to fast track the discovery of a breast cancer risk gene which could assist in the discovery of other cancer genes...
30.03.2012 22:00
Roche released an announcement today in regards to its phase three trial called EMILIA. The program compared performance of its new drug Trastuzumab Emtansine against standard treatments for HER2-positive Metastatic Breast Cancer that use lapatinib plus Xeloda® (capecitabine). Patients were enrolled in the study having previously received Herceptin® and ataxane (chemotherapy)...
30.03.2012 10:00
A new blood test is twice as sensitive and can detect breast cancer recurrence a full year earlier than current blood tests, according to a scientist who reported at the 243rd National Meeting & Exposition of the American Chemical Society (ACS)...
If the fight against breast cancer were a criminal investigation, then the proteins survivin, HDAC6, CBP, and CRM1 would be among the shadier figures. In that vein, a study to be published in the March 30 Journal of Biological Chemistry is the police report that reveals a key moment for keeping cancer cells alive: survivin's jailbreak from the nucleus, aided and abetted by the other proteins...
29.03.2012 18:00
The journal Alcohol and Alcoholism has published a new review of studies that have researched the association between alcohol consumption and breast cancer. The findings revealed that the risk of breast cancer rises by 5% for low level or moderate drinkers, i.e. women who have one drink per day, whilst the risk for those who consume three or more drinks daily (heavy consumption) is 40-50% higher...
29.03.2012 16:00
A study presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. shows that percutaneous cryoablation may be provide another treatment alternative for people suffering from metastatic breast cancer, in whom the disease has progressed to other areas of the body...
29.03.2012 10:00
Some breast cancer tumours may be resistant to a common chemotherapy treatment, suggests recent medical research at the University of Alberta. Principal investigator Ing Swie Goping and her team discovered some breast cancer tumours had low levels of certain genes, and that those tumours didn't respond well to taxane chemotherapy, a common treatment used in breast cancer...
28.03.2012 11:00
Nearly one in five people suffers from the insidious and often devastating problem of chronic pain. That the problem persists, and is growing, is striking given the many breakthroughs in understanding the basic biology of pain over the past two decades...
28.03.2012 10:00
Preoperative treatment with aromatase inhibitors increases the likelihood that postmenopausal women with estrogen receptor-positive breast cancer will be able to have breast-conserving surgery rather than a mastectomy, according to the results of a national clinical trial presented at the Society of Surgical Oncology annual meeting in Orlando, Fla...
27.03.2012 12:00
Individuals fighting metastatic breast cancer, where the disease has progressed to other areas of the body, may finally have another weapon in their arsenal: percutaneous cryoablation...
27.03.2012 10:00
Results from a phase III clinical trial evaluating a new treatment for breast cancer in post-menopausal women show that the combination of two cancer drugs, everolimus and exemestane, significantly improves bone strength and reduces the chances of cancer spreading (metastasising) in the bone...
The use of ultrasound-guided surgery to remove tumours from women who have palpable breast cancer is much more successful than standard surgery in excising all the cancerous tissue while sparing as much healthy tissue as possible, according to the results of a randomised controlled trial...
Women who are overweight or obese when they are diagnosed with breast cancer are at higher risk of cancer recurrence or related death than are leaner women, according to a new study to be presented to the 8th European Breast Cancer Conference (EBCC-8)...
26.03.2012 11:00
Researchers at Brown University have created an implant that appears to deter breast cancer cell regrowth. Made from a common federally approved polymer, the implant is the first to be modified at the nanoscale in a way that causes a reduction in the blood-vessel architecture that breast cancer tumors depend upon, while also attracting healthy breast cells. Results are published in Nanotechnology...
26.03.2012 10:00
Could blocking a testosterone receptor lead to a new way to treat an aggressive form of breast cancer? That's a question researchers at Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) are exploring...
The largest study ever on the effect of genetic variability on the toxicity of chemotherapy in breast cancer shows that it is possible to predict which patients are most likely to suffer serious side effects, a researchertold the 8th European Breast Cancer Conference (EBCC-8). Dr...
24.03.2012 09:00
Scientists have uncovered a marker of DNA damage that could predict who will respond to platinum-based chemotherapy drugs like cisplatin or carboplatin. These drugs are widely used for ovarian cancer, but as with most cancer drugs, it can be difficult to predict who will respond to therapy...
Every new imaging technology has an aura of magic about it because it suddenly reveals what had been concealed, and makes visible what had been invisible. So, too, with photoacoustic tomography, which is allowing scientists to virtually peel away the top several inches of flesh to see what lies beneath...
23.03.2012 10:00
A team of researchers led by Michael H. Antoni, director of the Center for Psycho-Oncology Research at the University of Miami (UM) has shown that a stress management program tailored to women with breast cancer can alter tumor-promoting processes at the molecular level...
Researchers from The Netherlands have found that the menopausal symptoms caused by giving chemotherapy or hormonal therapy to younger women with breast cancer can be ameliorated considerably through the use of cognitive behavioral therapy (CBT)[1] and physical exercise (PE)...
Radiotherapy treatment (RT) after surgery for ductal carcinoma in situ (DCIS) [1] still has a major protective effect against recurrence more than 15 years later, according to the results of an international trial. Researchers found that the use of RT in addition to surgery could reduce the chances of a local recurrence (the cancer coming back in the same breast) by 50%...
23.03.2012 09:00
Women diagnosed with ductal carcinoma in situ (DCIS) need clear communication and tailored support to enable them to understand this complex breast condition, which has divided the medical profession when it comes to its perception and prognosis. That is the key finding of a study published in the April issue of the Journal of Advanced Nursing...
Detecting the presence of circulating tumour cells (CTCs) in the blood of women with early breast cancer after surgery but before the start of chemotherapy can provide useful information about their chances of surviving the disease. CTCs are cancer cells which are detectable in patients with a solid tumour and their value in the prognosis of metastatic breast cancer has been known for a few years...
A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast...
Testing a breast cancer tumour for its genomic signature can help identify which patients will need adjuvant systemic therapy (additional chemotherapy) after surgery, and spare its use in those for whom it is not necessary, according to the results of a study presented to the 8th European Breast Cancer Conference (EBCC-8). Dr...
22.03.2012 10:00
Women aged 50 and over with breasts that have a high percentage of dense tissue are at greater risk of their breast cancer recurring, according to Swedish research presented at the eighth European Breast Cancer Conference (EBCC-8) in Vienna...
Results from one of the longest-running national breast cancer screening programmes have shown that it has contributed to a drop in deaths from the disease, that any harm caused by the screening, such as false positives and over-diagnosis, has been limited, and that the costs have been reasonable...
Adding magnetic resonance imaging (MRI) to standard breast cancer screening approaches is expensive, though it could be cost effective for a group of women who may not have inherited the breast cancer susceptibility genes, but who have a familial risk of developing the disease. This is the conclusion of research presented at the eighth European Breast Cancer Conference (EBCC-8)...
A Dutch study of the effectiveness of breast cancer screening shows that, even with improved treatments for the disease, population-based mammography programmes still save a significant number of lives...
22.03.2012 09:00
ONCOLOGY Promise of new treatment options for chemotherapy-resistant breast cancers p53 is lost or functionally impaired in many human cancers, and its absence is often associated with a poor response to conventional chemotherapy. Thus, much effort is currently devoted to developing novel treatments for p53-deficient malignancies...
21.03.2012 11:00
New research has shown for the first time that it is safe for women who have been diagnosed with oestrogen receptor positive breast cancer to become pregnant, despite doctors' previous fears that pregnancy could boost levels of oestrogen in the body and cause the cancer to return...
21.03.2012 09:00
Cytori Therapeutics (NASDAQ: CYTX) has announced the publication of RESTORE-2 trial results in the peer-reviewed European Journal of Surgical Oncology. RESTORE-2 is a 71 patient multi-center, prospective clinical trial using autologous adipose-derived regenerative cell (ADRC)-enriched fat grafting for reconstruction of the breast after cancer surgery...
20.03.2012 11:00
Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study published on March 19th in the Journal of Experimental Medicine. Triple-negative breast tumors lack all of the known growth receptors that serve as treatment targets in other types of breast cancer, making this the most clinically challenging subtype of the disease...
19.03.2012 09:00
Antibodies, once touted as the "magic bullets" of cancer care, are now fulfilling that promise and more advances are on the way, say cancer researchers at the Georgetown Lombardi Comprehensive Cancer Center In a review article posted online in Cell, the researchers say that refinements and modifications of monoclonal antibody drugs - several of which have already revolutioni...
Researchers from the National University of Singapore and National Cancer Centre Singapore found that Asian breast cancer patients turned to mahjong, qi gong and complementary alternative medicine to cope with cognitive changes...
18.03.2012 09:00
In the past decade, results from large prospective cohort studies and the Women's Health Initiative (WHI) randomized placebo-controlled hormone therapy trials have substantially changed thoughts about how estrogen alone and estrogen plus progestin influence the risk of breast cancer, according to a review published in the Journal of The National Cancer Institute...
17.03.2012 09:00
Rensselaer Polytechnic Institute Biologist Lee Ligon has found a previously unknown connection between breast cancer tumor cells and the surrounding healthy tissue. The results provide new information on the earliest stages of breast cancer metastasis...
16.03.2012 18:00
According to a study published March 15 in the Journal of the National Cancer Institute, thoughts about how estrogen alone or estrogen in addition to progestin influence the risk of developing breast cancer has considerably changed in the past 10 years due to results from the Women's Health Initiative (WHI) randomized placebo-controlled hormone therapy trials, and from large p...
16.03.2012 09:00
A new study by University of Kentucky researchers provides insight into developing new treatment strategies for basal-like breast cancer, commonly known as triple negative breast cancer. This cancer is associated with early metastasis and resistance to chemotherapy and occurs at women at a younger age...
A recent study, published in Cancer Research , a journal of the American Association for Cancer Research, explains that dietary cadmium, which is a metal found in fertilizers used on farms and is very toxic, can potentially pose a risk of breast cancer. Agneta Akesson, Ph...
13.03.2012 10:00
ONCOLOGY New Determinant of Human Breast Cancer Metastasis Discovered Researchers at the University of Kentucky's Markey Cancer Center in Lexington, KY have provided new insight as to why the most severe subtype of breast cancer in humans frequently metastasizes...
12.03.2012 10:00
Rowan T. Chlebowski, M.D., Ph.D...
11.03.2012 09:00
Sientra Inc's silicone gel-filled breast implant for breast reconstruction or augmentation has been approved by the FDA, as long as the company carries out post-approval studies to assess the device's long-term effectiveness, safety, and rare disease outcomes. The implant is approved for females aged at least 22 years...
08.03.2012 10:00
In particularly aggressive forms of breast cancer, cancer cells can settle in other organs and form metastases there. Once such metastases form, complete recovery is rare. Consequently, it is enormously important to prevent the metastasisation of the breast cancer cells. The success, however, achieved by using existing forms of therapy is limited...
Purdue University researchers have created a new imaging technology that reveals subtle changes in breast tissue, representing a potential tool to determine a woman's risk of developing breast cancer and to study ways of preventing the disease...
Two studies published in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the usefulness of CYP2D6 testing for deciding whether or not a patient should receive adjuvant tamoxifen for treatment of early-stage breast cancer...
08.03.2012 09:00
07.03.2012 19:00
A study published in The Lancet Oncology, shows women taking Hormone Replacement Therapy (HRT) are less likely to develop breast cancer. Researchers from the Fred Hutchinson Cancer Research Center, Seattle, USA looked at data from more than 7,500 women who were enrolled in the Women's Health Initiative (WHI) trial and took HRT over a period of about six years...
07.03.2012 10:00
Every day 18 Swedish women are diagnosed with breast cancer. Although there is a real need for support and information, many women struggle and get lost in the deluge of information. In a study of 227 women, researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have developed a web-based programme to guide patients all the way from diagnosis to rehabilitation...
In this week's PLoS Medicine, a case-control study conducted by Margaret Urban and colleagues at the National Health Laboratory Services in Johannesburg, South Africa, provides new estimates of the risk of specific cancers of the female reproductive system associated with use of injectable and oral contraceptives...
06.03.2012 10:00
Even though a large clinical study demonstrated that radiation has limited benefit in treating breast cancer in some older women, there was little change in the use of radiation among older women in the Medicare program, Yale School of Medicine researchers report in the March Journal of Clinical Oncology. "We were surprised by these results," said lead author Cary P. Gross, M.D...
06.03.2012 09:00
Scientists have successfully completed an initial trial of a new, potentially more reliable, technique for screening breast cancer using ultrasound. The team at the National Physical Laboratory (NPL), the UK's National Measurement Institute, working with the University Hospitals Bristol NHS Foundation Trust, are now looking to develop the technique into a clinical device...
03.03.2012 09:00
The main cause of death in women with breast cancer is spread of the original tumor to distant sites, a process known as metastasis. New therapeutic targets are urgently needed...
02.03.2012 09:00
Breast cancer represents about a fifth of all cancers diagnosed in women and despite significant advances in therapy it continues to cause the death of many of the sufferers - nearly half a million worldwide in 2008...
01.03.2012 14:00
T he American Cancer Society estimates that this year alone, 229,060 Americans will be diagnosed with breast cancer and 39,920 patients will die from the disease. Almost one in three women with breast cancer surgery will require additional surgery, following a pathologic examination of their tumor...
01.03.2012 09:00
Nearly one in three women who have breast cancer surgery will need to return to the operating room for additional surgery after the tumor is evaluated by a pathologist. A new service at the University of Michigan Comprehensive Cancer Center cuts that number drastically by having pathologists on-site in the operating suite to assess tumors and lymph nodes immediately after they are removed...
As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention. As part of the national Breast Cancer Surveillance Consortium, researchers studied 741,681 woman-years of data (with a median of 3...
29.02.2012 14:00
A new study suggests that quitting hormone therapy (HT) has an immediate effect on breast cancer rates, supporting the idea that stopping it leads to tumor regression...
29.02.2012 11:00
Although the actual number of people predicted to die from cancer in the European Union (EU) this year will increase, the rates of cancer deaths (calculated as per 100,000 of the population, by age group) continue to fall, according to new figures published on Tuesday. The sharpest falls are in breast cancer rates...
28.02.2012 13:00
A study headed up by the Vall d'Hebron Institute of Oncology (VHIO) heralds a new horizon in the fight against cancer, opening up a parallel dimension to existing treatment options...
28.02.2012 12:00
Dutch investigators have reported that women who received CMF chemotherapy (a combination regimen including the drugs cyclophosphamide, methotrexate, and 5-fluorouracil) for breast cancer between 1976 and 1995 scored worse on cognitive tests than women who never had cancer...
27.02.2012 10:00
You probably know your blood type: A, B, AB or O. You may even know if you're Rhesus positive or negative. But how about the Langereis blood type? Or the Junior blood type? Positive or negative? Most people have never even heard of these. Yet this knowledge could be "a matter of life and death," says University of Vermont biologist Bryan Ballif...
26.02.2012 09:00
Although it's widely accepted that inflammation is a critical underlying factor in a range of diseases, including the progression of cancer, little is known about its role when normal cells become tumor cells...
24.02.2012 10:00
Oncologists have known that in order for cancer cells to spread, they must transform themselves so they can detach from a tumor and spread to a distant organ. Now, scientists at Weill Cornell Medical College have revealed critical steps in what happens next - how these cells reverse the process, morphing back into classical cancer that can now grow into a new tumor...
23.02.2012 11:00
The infamous BRCA genes do not act alone in causing cancer; there is a molecular syndicate at work preventing the way cells normally repair breaks in DNA that is at the root of breast cancer. But finding all of the BRCA molecular collaborators has been elusive...
23.02.2012 09:00
Based on a study of nearly 2,000 breast cancer patients, researchers at the Swedish Cancer Institute in Seattle say that, in women between the ages of 40 and 49, breast cancers detected by mammography have a better prognosis. The study appears in the March issue of Radiology...
21.02.2012 10:00
Blocking autophagy - the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments. Specifically, blocking the action of an acidic inner cell part, which acts like a stomach and chews up proteins for recycling, is the main attack strategy, says Ravi K...
20.02.2012 10:00
Signals can tell cells to act cancerous, surviving, growing and reproducing out of control. And signals can also tell cells with cancerous characteristics to stop growing or to die. In breast cancer, one tricky signal called TGF-beta does both - sometimes promoting tumors and sometimes suppressing them...
18.02.2012 10:00
A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross- a "library" of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discov...
The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade tumors and therefore associated with features of a good prognosis, it has a more sinister role in breast cancer invasion and metastasis...
16.02.2012 11:00
GW Cancer Research Team in the Department of Biochemistry and Molecular Biology, in the School of Medicine and Health Sciences, published a study that is the first of its kind to use mRNA sequencing to look at the expression of genome, at a unprecedented resolution at the current time, in three types of breast cancer...
16.02.2012 10:00
Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy...
16.02.2012 00:00
Two new studies state that cognitive behavioral therapy (CBT) has been proven to help treat menopause symptoms, including night sweats and hot flushes. Cognitive behavioral therapy is a method using a psychotherapeutic approach - a talking approach...
15.02.2012 11:00
A new prospective study of patients with Lynch syndrome - an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes - provides the first strong evidence that people with Lynch syndrome face significantly increased risks of breast and pancreatic cancers...
14.02.2012 20:00
Inflammatory breast cancer (IBC) spreads easily through the lymphatic and blood vessels, forming metastasis, which can cause several organs in the body to fail, IBC is also the deadliest form of breast cancer...
14.02.2012 13:00
Breast cancers expressing the protein HER2 have a particularly poor prognosis. Treatment with trastuzumab (Herceptin) benefits some patients with HER2-positive breast cancer, but it is not as effective as had been hoped. Researchers are therefore seeking ways to enhance the effectiveness of trastuzumab...
14.02.2012 10:00
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer. It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure...
13.02.2012 10:00
Wake Forest Baptist Medical Center researchers have again proven that injecting multiwalled carbon nanotubes (MWCNTs) into tumors and heating them with a quick, 30-second laser treatment can kill them...
10.02.2012 10:00
Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people...
Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness of invasive tumors, and with the time to metastasis and overall survival. Researchers at the Ohio State University Comprehensive Cancer Center - Arthur G...
09.02.2012 19:00
A study in the February 8 edition of JAMA shows that postmenopausal women who suffer from hormone receptor-positive breast cancer have a higher death risk of breast cancer as they get older. Background information in the article states that: "Breast cancer is the leading contributor to cancer incidence and cancer mortality in women worldwide, with 1,383,500 new cases in 2008...
09.02.2012 12:00
Man may not live by bread alone, but cancer in animals appears less resilient, judging by a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting. Even fasting on its own effectively treated a majority of cancers tested in animals, including cancers from human cells...
08.02.2012 20:00
A study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, reveals that breast cancer cell proliferation was not lowered with soy isoflavone supplements in a randomized human trial. Isoflavone are components of soy foods believed to have anti-estrogen activity...
08.02.2012 10:00
A new study analyses the influence that certain birth and infancy characteristics have on mammographic density - an important indicator of breast cancer risk. The results reveal that women born to mothers aged over 39 years and women who were taller and thinner than the average girl prior to puberty have a higher breast density. This brings with it an increased risk of developing breast cancer...
The body's control mechanisms for delivering zinc to cells could be key to improving treatment for some types of aggressive breast cancer. New research by Cardiff University and King's College London has identified the switch which releases zinc into cells, with important implications for a number of diseases. Zinc has long been known to play a vital part in human health...
In two new studies featured in the February issue of The Journal of Nuclear Medicine, researchers are revealing how molecular imaging can be used to solve mysteries about difficult cases of breast cancer...
07.02.2012 11:00
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD...
07.02.2012 10:00
The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects...
Soy isoflavone supplements did not decrease breast cancer cell proliferation in a randomized clinical trial, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Lead researcher Seema A. Khan, M.D., professor of surgery at the Robert H...
07.02.2012 04:00
A recent study published in The Lancet Oncology shows how exemestane (Aromasin), a drug that prevents the development of breast cancer in postmenopausal women, may significantly worsen age-related bone loss. As an aromatase inhibitor, exemestane works by blocking the synthesis of estrogen, slowing down the growth of cancers that have estrogen receptors...
06.02.2012 00:00
Susan G. Komen for the Cure, a breast cancer charity which until recently had an enviable reputation as being totally impartial and focused purely on saving women's lives, may have caused itself irreparable damage. By announcing a few days ago that it would stop awarding funds to Planned Parenthood, a sexual health organization; it found itself in the middle of an enormous public outcry...
03.02.2012 21:00
According to an investigation in the February 1 issue of JAMA, surgery to remove additional tissue (reexcision) is required in almost 1 in 4 women who undergo a partial mastectomy for breast cancer treatment. In addition, there is considerable surgeon and institutional difference in the rate of reexcisions that have nothing to do with patients' characteristics. In the U.S...
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