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Cancer Gene Therapy - AOP

Cancer Gene Therapy is the essential gene therapy resource for cancer researchers and clinicians, keeping readers up to date with the latest developments in gene therapy for cancer.

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Combining transfer of TTF-1 and Pax-8 gene: a potential strategy to promote radioiodine therapy of thyroid carcinoma Quick resume for : Combining transfer of TTF-1 and Pax-8 gene: a potential strategy to promote radioiodine therapy of thyroid carcinoma

13.04.2012 00:00

The radiation dose-regulated AND gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy Quick resume for : The radiation dose-regulated AND gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy

13.04.2012 00:00

Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer Quick resume for : Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer

13.04.2012 00:00

Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models Quick resume for : Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models

13.04.2012 00:00

Induced transgene expression for the treatment of solid tumors by hematopoietic stem cell-based gene therapy Quick resume for : Induced transgene expression for the treatment of solid tumors by hematopoietic stem cell-based gene therapy

09.03.2012 00:00

Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells Quick resume for : Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells

09.03.2012 00:00

Membrane-bound form of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy in a model of hepatocellular carcinoma Quick resume for : Membrane-bound form of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy in a model of hepatocellular carcinoma

09.03.2012 00:00

Intratumoral delivery of CD154 homolog (Ad-ISF35) induces tumor regression: analysis of vector biodistribution, persistence and gene expression Quick resume for : Intratumoral delivery of CD154 homolog (Ad-ISF35) induces tumor regression: analysis of vector biodistribution, persistence and gene expression

09.03.2012 00:00

An artificially constructed radiation-responsive promoter is activated by doxorubicin Quick resume for : An artificially constructed radiation-responsive promoter is activated by doxorubicin

09.03.2012 00:00

Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma Quick resume for : Antitumor potential of SLPI promoter controlled recombinant caspase-3 expression in laryngeal carcinoma

02.03.2012 00:00

Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer Quick resume for : Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer

02.03.2012 00:00

Targeting dendritic cells with antigen via dendritic cell-associated promoters Quick resume for : Targeting dendritic cells with antigen via dendritic cell-associated promoters

24.02.2012 00:00

Germ cell DNA-repair systems—possible tools in cancer research? Quick resume for : Germ cell DNA-repair systems—possible tools in cancer research?

10.02.2012 00:00

Complementary treatment of siTERT for improving the antitumor effect of TERT-specific I-131 therapy Quick resume for : Complementary treatment of siTERT for improving the antitumor effect of TERT-specific I-131 therapy

03.02.2012 00:00

Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes Quick resume for : Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes

27.01.2012 00:00

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells Quick resume for : Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells

27.01.2012 00:00

Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model Quick resume for : Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model

27.01.2012 00:00

Treatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells Quick resume for : Treatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells

13.01.2012 00:00

Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed Quick resume for : Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed

06.01.2012 00:00

Targeting 14-3-3zeta in cancer therapy Quick resume for : Targeting 14-3-3zeta in cancer therapy

23.12.2011 00:00

A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy Quick resume for : A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy

23.12.2011 00:00

Impact of novel oncolytic virus HF10 on cellular components of the tumor microenviroment in patients with recurrent breast cancer Quick resume for : Impact of novel oncolytic virus HF10 on cellular components of the tumor microenviroment in patients with recurrent breast cancer

23.12.2011 00:00

Immunotherapy targeting HER2 with genetically modified T cells eliminates tumor-initiating cells in osteosarcoma Quick resume for : Immunotherapy targeting HER2 with genetically modified T cells eliminates tumor-initiating cells in osteosarcoma

16.12.2011 00:00

The antitumor effects of adenoviral-mediated, intratumoral delivery of interleukin 23 require endogenous IL-12 Quick resume for : The antitumor effects of adenoviral-mediated, intratumoral delivery of interleukin 23 require endogenous IL-12

09.12.2011 00:00

Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity Quick resume for : Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity

09.12.2011 00:00

Mc-hES, a novel plasmid carrying human endostatin gene, inhibits nasopharyngeal carcinoma growth Quick resume for : Mc-hES, a novel plasmid carrying human endostatin gene, inhibits nasopharyngeal carcinoma growth

09.12.2011 00:00

Oncolytic poxvirus armed with Fas ligand leads to induction of cellular Fas receptor and selective viral replication in FasR-negative cancer Quick resume for : Oncolytic poxvirus armed with Fas ligand leads to induction of cellular Fas receptor and selective viral replication in FasR-negative cancer

25.11.2011 00:00

E10A, an adenovirus-carrying endostatin gene, dramatically increased the tumor drug concentration of metronomic chemotherapy with low-dose cisplatin in a xenograft mouse model for head and neck squamous-cell carcinoma Quick resume for : E10A, an adenovirus-carrying endostatin gene, dramatically increased the tumor drug concentration of metronomic chemotherapy with low-dose cisplatin in a xenograft mouse model for head and neck squamous-cell carcinoma

25.11.2011 00:00

Polyinosinic acid decreases sequestration and improves systemic therapy of measles virus Quick resume for : Polyinosinic acid decreases sequestration and improves systemic therapy of measles virus

25.11.2011 00:00

Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development Quick resume for : Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development

18.11.2011 00:00

Sonoporation-mediated anti-angiogenic gene transfer into muscle effectively regresses distant orthotopic tumors Quick resume for : Sonoporation-mediated anti-angiogenic gene transfer into muscle effectively regresses distant orthotopic tumors

18.11.2011 00:00

Oncolytic Herpes simplex virus expressing yeast cytosine deaminase: relationship between viral replication, transgene expression, prodrug bioactivation Quick resume for : Oncolytic Herpes simplex virus expressing yeast cytosine deaminase: relationship between viral replication, transgene expression, prodrug bioactivation

11.11.2011 00:00

Efficient antitumor effects of carrier cells loaded with a fiber-substituted conditionally replicating adenovirus on CAR-negative tumor cells Quick resume for : Efficient antitumor effects of carrier cells loaded with a fiber-substituted conditionally replicating adenovirus on CAR-negative tumor cells

11.11.2011 00:00

Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus Quick resume for : Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus

11.11.2011 00:00

VSV-MP gene therapy strategy inhibits tumor growth in nude mice model of human lung adenocarcinoma Quick resume for : VSV-MP gene therapy strategy inhibits tumor growth in nude mice model of human lung adenocarcinoma

04.11.2011 00:00

The chicken chorioallantoic membrane tumor assay as model for qualitative testing of oncolytic adenoviruses Quick resume for : The chicken chorioallantoic membrane tumor assay as model for qualitative testing of oncolytic adenoviruses

21.10.2011 00:00

Molecular network pathways and functional analysis of tumor signatures associated with development of resistance to viral gene therapy Quick resume for : Molecular network pathways and functional analysis of tumor signatures associated with development of resistance to viral gene therapy

21.10.2011 00:00

Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function Quick resume for : Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function

14.10.2011 00:00

CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model Quick resume for : CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model

14.10.2011 00:00

Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor Quick resume for : Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor

07.10.2011 00:00

Gene-viro-therapy targeting liver cancer by a dual-regulated oncolytic adenoviral vector harboring IL-24 and TRAIL Quick resume for : Gene-viro-therapy targeting liver cancer by a dual-regulated oncolytic adenoviral vector harboring IL-24 and TRAIL

07.10.2011 00:00

Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xenografted in mice Quick resume for : Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xenografted in mice

30.09.2011 00:00

D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate Quick resume for : D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate

16.09.2011 00:00

Fibroblast growth factor and ornithine decarboxylase 5′UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN−/− transgenic mice Quick resume for : Fibroblast growth factor and ornithine decarboxylase 5′UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN−/− transgenic mice

16.09.2011 00:00

Antitumor effect of sFlt-1 gene therapy system mediated by Bifidobacterium Infantis on Lewis lung cancer in mice Quick resume for : Antitumor effect of sFlt-1 gene therapy system mediated by Bifidobacterium Infantis on Lewis lung cancer in mice

16.09.2011 00:00

Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability Quick resume for : Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability

09.09.2011 00:00

Treatment of mesothelioma with gene-modified PA1STK cells and ganciclovir: a phase I study Quick resume for : Treatment of mesothelioma with gene-modified PA1STK cells and ganciclovir: a phase I study

09.09.2011 00:00

Vesicular stomatitis virus as a treatment for colorectal cancer Quick resume for : Vesicular stomatitis virus as a treatment for colorectal cancer

02.09.2011 00:00

Mining the adenovirus virome for oncolytics against multiple solid tumor types Quick resume for : Mining the adenovirus virome for oncolytics against multiple solid tumor types

02.09.2011 00:00

Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models Quick resume for : Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models

26.08.2011 00:00

Effect of fractalkine-Fc delivery in experimental lung metastasis using DNA/704 nanospheres Quick resume for : Effect of fractalkine-Fc delivery in experimental lung metastasis using DNA/704 nanospheres

26.08.2011 00:00

SV40 T/t-common polypeptide inhibits angiogenesis and growth of HER2-overexpressing human ovarian cancer Quick resume for : SV40 T/t-common polypeptide inhibits angiogenesis and growth of HER2-overexpressing human ovarian cancer

26.08.2011 00:00

Virotherapy induces massive infiltration of neutrophils in a subset of tumors defined by a strong endogenous interferon response activity Quick resume for : Virotherapy induces massive infiltration of neutrophils in a subset of tumors defined by a strong endogenous interferon response activity

26.08.2011 00:00

Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists Quick resume for : Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists

26.08.2011 00:00

EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene Quick resume for : EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene

26.08.2011 00:00

Therapeutic targeting of subdural medulloblastomas using human neural stem cells expressing carboxylesterase Quick resume for : Therapeutic targeting of subdural medulloblastomas using human neural stem cells expressing carboxylesterase

26.08.2011 00:00

Unrepairable DNA double-strand breaks initiate cytotoxicity with HSV-TK/ganciclovir Quick resume for : Unrepairable DNA double-strand breaks initiate cytotoxicity with HSV-TK/ganciclovir

26.08.2011 00:00

Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver Quick resume for : Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver

19.08.2011 00:00

Oncolytic adenovirus armed with human papillomavirus E2 gene in combination with radiation demonstrates synergistic enhancements of antitumor efficacy Quick resume for : Oncolytic adenovirus armed with human papillomavirus E2 gene in combination with radiation demonstrates synergistic enhancements of antitumor efficacy

19.08.2011 00:00

An oncolytic adenovirus defective in pRb-binding (dl922–947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine Quick resume for : An oncolytic adenovirus defective in pRb-binding (dl922–947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine

12.08.2011 00:00

Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses: implications for the generation of ideal m-CRAs Quick resume for : Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses: implications for the generation of ideal m-CRAs

12.08.2011 00:00

Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo Quick resume for : Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo

12.08.2011 00:00

Selective modification of HK peptides enhances siRNA silencing of tumor targets in vivo Quick resume for : Selective modification of HK peptides enhances siRNA silencing of tumor targets in vivo

05.08.2011 00:00

Deletion analysis of Ad5 E1a transcriptional control region: impact on tumor-selective expression of E1a and E1b Quick resume for : Deletion analysis of Ad5 E1a transcriptional control region: impact on tumor-selective expression of E1a and E1b

05.08.2011 00:00

Inhibitory effects of interferon-gamma plasmid DNA on DMBA-TPA induced mouse skin carcinogenesis Quick resume for : Inhibitory effects of interferon-gamma plasmid DNA on DMBA-TPA induced mouse skin carcinogenesis

29.07.2011 00:00

Comparison of distribution and activity of nanoparticles with short interfering DNA (Dbait) in various living systems Quick resume for : Comparison of distribution and activity of nanoparticles with short interfering DNA (Dbait) in various living systems

29.07.2011 00:00

Gap junctions in human glioblastomas: implications for suicide gene therapy Quick resume for : Gap junctions in human glioblastomas: implications for suicide gene therapy

22.07.2011 00:00

Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32 Quick resume for : Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32

15.07.2011 00:00

Application of mRNA regulatory regions to improve tumor specificity of transgene expression Quick resume for : Application of mRNA regulatory regions to improve tumor specificity of transgene expression

01.07.2011 00:00

Screening siRNAs targeting a novel gene (HA117) and the development of a derivative recombinant adenovirus delivery system Quick resume for : Screening siRNAs targeting a novel gene (HA117) and the development of a derivative recombinant adenovirus delivery system

01.07.2011 00:00

Baculovirus vectors for antiangiogenesis-based cancer gene therapy Quick resume for : Baculovirus vectors for antiangiogenesis-based cancer gene therapy

24.06.2011 00:00

Armed and targeted measles virus for chemovirotherapy of pancreatic cancer Quick resume for : Armed and targeted measles virus for chemovirotherapy of pancreatic cancer

24.06.2011 00:00

Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1 Quick resume for : Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1

24.06.2011 00:00

Direct cytotoxicity produced by adenoviral-mediated interferon α gene transfer in interferon-resistant cancer cells involves ER stress and caspase 4 activation Quick resume for : Direct cytotoxicity produced by adenoviral-mediated interferon α gene transfer in interferon-resistant cancer cells involves ER stress and caspase 4 activation

17.06.2011 00:00

Enhanced specificity of HPV16 E6E7 siRNA by RNA–DNA chimera modification Quick resume for : Enhanced specificity of HPV16 E6E7 siRNA by RNA–DNA chimera modification

10.06.2011 00:00

Competitive electroporation formulation for cell therapy Quick resume for : Competitive electroporation formulation for cell therapy

10.06.2011 00:00

Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma Quick resume for : Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma

10.06.2011 00:00

DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma Quick resume for : DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma

10.06.2011 00:00

Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells Quick resume for : Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells

10.06.2011 00:00

Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial–mesenchymal transition Quick resume for : Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial–mesenchymal transition

03.06.2011 00:00

Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells Quick resume for : Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells

20.05.2011 00:00

The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells Quick resume for : The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells

13.05.2011 00:00

Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8+ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice Quick resume for : Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8+ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice

13.05.2011 00:00

Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy Quick resume for : Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy

13.05.2011 00:00

Induction of the glucocorticoid-induced leucine zipper gene limits the efficacy of dendritic cell vaccines Quick resume for : Induction of the glucocorticoid-induced leucine zipper gene limits the efficacy of dendritic cell vaccines

06.05.2011 00:00

MDA-7 results in downregulation of AKT concomitant with apoptosis and cell cycle arrest in breast cancer cells Quick resume for : MDA-7 results in downregulation of AKT concomitant with apoptosis and cell cycle arrest in breast cancer cells

06.05.2011 00:00

Docetaxel plus trans-tracheal injection of adenoviral-mediated p53 versus docetaxel alone in patients with previously treated non-small-cell lung cancer Quick resume for : Docetaxel plus trans-tracheal injection of adenoviral-mediated p53 versus docetaxel alone in patients with previously treated non-small-cell lung cancer

01.04.2011 00:00

Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells Quick resume for : Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells

01.04.2011 00:00

In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis Quick resume for : In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis

25.03.2011 00:00

RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells Quick resume for : RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells

25.03.2011 00:00

Clinical development directions in oncolytic viral therapy Quick resume for : Clinical development directions in oncolytic viral therapy

25.03.2011 00:00

Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models Quick resume for : Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models

11.03.2011 00:00

The tumor suppressor function of LECT2 in human hepatocellular carcinoma makes it a potential therapeutic target Quick resume for : The tumor suppressor function of LECT2 in human hepatocellular carcinoma makes it a potential therapeutic target

11.03.2011 00:00

Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase Quick resume for : Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase

11.03.2011 00:00

Comparative analysis of enzyme and pathway engineering strategies for 5FC-mediated suicide gene therapy applications Quick resume for : Comparative analysis of enzyme and pathway engineering strategies for 5FC-mediated suicide gene therapy applications

11.03.2011 00:00

Role of temperature-independent lipoplex–cell membrane interactions in the efficiency boost of multicomponent lipoplexes Quick resume for : Role of temperature-independent lipoplex–cell membrane interactions in the efficiency boost of multicomponent lipoplexes

11.03.2011 00:00

Enhancing VSV oncolytic activity with an improved cytosine deaminase suicide gene strategy Quick resume for : Enhancing VSV oncolytic activity with an improved cytosine deaminase suicide gene strategy

11.03.2011 00:00

Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma Quick resume for : Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma

11.03.2011 00:00

Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma Quick resume for : Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma

04.03.2011 00:00

Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery Quick resume for : Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery

04.03.2011 00:00

Enhancement of CPT-11 antitumor activity by adenovirus-mediated expression of β–glucuronidase in tumors Quick resume for : Enhancement of CPT-11 antitumor activity by adenovirus-mediated expression of β–glucuronidase in tumors

25.02.2011 00:00

Pre-clinical toxicity assessment of tumor-targeted interleukin-12 low-intensity electrogenetherapy Quick resume for : Pre-clinical toxicity assessment of tumor-targeted interleukin-12 low-intensity electrogenetherapy

14.01.2011 00:00

Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma Quick resume for : Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma

14.01.2011 00:00

Effects of RNA interference targeting four different genes on the growth and proliferation of nasopharyngeal carcinoma CNE-2Z cells Quick resume for : Effects of RNA interference targeting four different genes on the growth and proliferation of nasopharyngeal carcinoma CNE-2Z cells

14.01.2011 00:00

Engineering a waste management enzyme to overcome cancer resistance to apoptosis: adding DNase1 to the anti-cancer toolbox Quick resume for : Engineering a waste management enzyme to overcome cancer resistance to apoptosis: adding DNase1 to the anti-cancer toolbox

14.01.2011 00:00

An Ad5[E1-, E2b-]-HER2/neu vector induces immune responses and inhibits HER2/neu expressing tumor progression in Ad5 immune mice Quick resume for : An Ad5[E1-, E2b-]-HER2/neu vector induces immune responses and inhibits HER2/neu expressing tumor progression in Ad5 immune mice

14.01.2011 00:00

Retargeting adenoviral vectors to improve gene transfer into tumors Quick resume for : Retargeting adenoviral vectors to improve gene transfer into tumors

24.12.2010 00:00

Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus Quick resume for : Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus

24.12.2010 00:00

Oncolytic adenovirus based on serotype 3 Quick resume for : Oncolytic adenovirus based on serotype 3

24.12.2010 00:00

Direct gene transfer of adenoviral-mediated interferon α into human bladder cancer cells but not the bystander factors produced induces endoplasmic reticulum stress-related cytotoxicity Quick resume for : Direct gene transfer of adenoviral-mediated interferon α into human bladder cancer cells but not the bystander factors produced induces endoplasmic reticulum stress-related cytotoxicity

24.12.2010 00:00

Transfection of NF-κB decoy oligodeoxynucleotide suppresses pulmonary metastasis by murine osteosarcoma Quick resume for : Transfection of NF-κB decoy oligodeoxynucleotide suppresses pulmonary metastasis by murine osteosarcoma

24.12.2010 00:00

Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells Quick resume for : Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells

26.11.2010 00:00

Novel adenovirus-based helper system to support production of recombinant parvovirus Quick resume for : Novel adenovirus-based helper system to support production of recombinant parvovirus

19.11.2010 00:00

Inhibition of cervical cancer cell growth in vitro and in vivo with dual shRNAs Quick resume for : Inhibition of cervical cancer cell growth in vitro and in vivo with dual shRNAs

19.11.2010 00:00

A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer Quick resume for : A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer

19.11.2010 00:00

In vitro and in vivo studies of adenovirus-mediated human norepinephrine transporter gene transduction to hepatocellular carcinoma Quick resume for : In vitro and in vivo studies of adenovirus-mediated human norepinephrine transporter gene transduction to hepatocellular carcinoma

12.11.2010 00:00

Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells Quick resume for : Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells

05.11.2010 00:00

Combining radiation therapy with interstitial radiation-inducible TNF-α expression for locoregional cancer treatment Quick resume for : Combining radiation therapy with interstitial radiation-inducible TNF-α expression for locoregional cancer treatment

05.11.2010 00:00

Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter Quick resume for : Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter

29.10.2010 00:00

Role of Rac1-dependent NADPH oxidase in the growth of pancreatic cancer Quick resume for : Role of Rac1-dependent NADPH oxidase in the growth of pancreatic cancer

29.10.2010 00:00

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