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19.04.2012 22:00
Part of an oral presentation at the recent Society of Surgical Oncology's 65th Annual Cancer Symposium in Orlando, revealed that a stratification of age, race and hormone receptor status helps to predict survival in node-negative breast cancer patients...
According to a new report, the '2025 Challenge: Saving and Improving Lives' from Bowel Cancer UK, the Government could reduce bowel cancer deaths by 60% by 2025, if it follows the recommendations of its new report. In the UK, bowel cancer is the second largest cancer killer, with an overall five-year survival rate of just over 50% of those who are diagnosed...
19.04.2012 20:00
Proton accelerators to treat cancer are described as the "most costly medical devices" in the world, and the UK and United States are investing considerable amounts of money in order to build them. However, journalist Keith Epstein states: "no clear evidence of better effectiveness exists" and that this investment may be premature...
19.04.2012 19:00
According to an evaluation of Medicare beneficiaries, there has been a significant increase in surgical treatment for nonmelanoma skin cancer (NMSC), from 2001 until 2006. The study, published in the April issue of Archives of Dermatology, states that the increase is primarily due to a doubling in the rate of Mohs micrographic surgery procedures...
19.04.2012 13:00
Breast cancer is at least 10 different diseases, each with its own genetic signature and pattern of weak spots, according to a new landmark study that promises to revolutionize diagnosis and prognosis, and pave the way for individualized, tailored treatment...
19.04.2012 11:00
A Michigan State University surgeon is teaming up with a Lansing-area dental benefits firm on a clinical trial to create a simple, cost-effective saliva test to detect oral cancer, a breakthrough that would drastically improve screening and result in fewer people dying of the world's sixth most common cancer...
19.04.2012 10:00
A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients suffered from recurrent glioblastoma multiforme - which kills thousands of Americans every year...
18.04.2012 23:00
The April issue of Archives of Otolaryngology - Head & Neck Surgery reports that patients who undergo chemoradiation therapy (CRT), who perform specific swallowing exercises after their CRT, experience a short-term improvement in swallowing...
18.04.2012 21:00
Researchers from The University of Texas MD Anderson Cancer Center have found that over 33.3% of individuals suffering from invasive cancer do not receive sufficient pain medication, with minorities twice as likely not to receive analgesics...
18.04.2012 13:00
About 71,500 women in the United States are diagnosed with a gynecologic cancer every year, according to the Centers for Disease Control. Researchers from University Hospitals Case Medical Center have developed a more effective way to treat gynecologic cancers, shortening radiation treatment time from five weeks to three days...
18.04.2012 11:00
More than one third of patients with invasive cancer are undertreated for their pain, with minorities twice as likely to not receive analgesics, according to research from The University of Texas MD Anderson Cancer Center. The study, published in Journal of Clinical Oncology, is the largest prospective evaluation of cancer pain and related symptoms ever conducted in an outpatient setting...
18.04.2012 10:00
A research team pursuing one of the most commonly altered genes in cancer has laid a critical foundation for understanding this gene that could point the way toward developing drugs against it. A recent study of cancer genetics pointed to the gene MCL1, which encodes a protein that helps keep cells alive...
17.04.2012 22:00
A study published in the April 18 issue of JAMA, reveals that Medicare insured non-small cell lung cancer (NSCLC) patients aged 65+, who received bevacizumab, in addition to the standard chemotherapy regimen carboplatin and paclitaxel, did not have improved survival compared to patients who received carboplatin and paclitaxel alone...
17.04.2012 15:00
It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction of cancer cells with their immediate surroundings, called the tumor microenvironment...
17.04.2012 13:00
AUTOIMMUNITY Understanding bone loss in rheumatoid arthritis patients Rheumatoid arthritis causes joint stiffness and pain for over 2 million Americans. The disease is caused by an errant attack on healthy tissue by the body's immune system...
New research at the University of Cincinnati (UC) suggests that kidney cancer growth depends on autophagy, a complex process that can provide cells with nutrients from intracellular sources. Researchers say in certain circumstances autophagy can protect tumor cells from chemotherapy, allowing them to survive for long periods of time in a hidden, dormant, metastatic state...
17.04.2012 10:00
Cancer is much more likely in the elderly than the young, and their bodies often are less prepared to fight the disease and the often-toxic side effects of treatment...
In a paper published in the journal Nature Methods, a team from the University of North Carolina at Chapel Hill demonstrates a simple, cost-effective technique for three-dimensional RNA structure prediction that will help scientists understand the structures, and ultimately the functions, of the RNA molecules that dictate almost every aspect of human cell behavior...
Like special-forces troops laser-tagging targets for a bomber pilot, tiny particles that can be imaged three different ways at once have enabled Stanford University School of Medicine scientists to remove brain tumors from mice with unprecedented accuracy...
16.04.2012 22:00
A new study by researchers at Montefiore Medical Center reveals that the incidence of anal carcinoma (AC) is increasing among HIV-positive women. The study entitled "High Prevalence of High Grade Anal Intraepithelial Neoplasia in HIV-Infected Women Screened for Anal Cancer" will appear in the Journal of Aids on May 1st, and was conducted from March 2008 to December 2010. Mark H...
16.04.2012 19:00
An international study published in the April 12 issue of the New England Journal of Medicine reports that bone marrow transplants are not the best option for some young patients with acute lymphoblastic leukemia (ALL) who fail to achieve clinical remission following their induction therapy of intense chemotherapy...
16.04.2012 11:00
Researchers at the University of Hull in the UK have identified a family of proteins that could potentially be used as biomarkers to predict resistance to chemotherapy in estrogen receptor-positive (ER-positive) breast cancer patients...
16.04.2012 10:00
Loyola researchers are reporting surprising findings about a molecule that helps ramp up the immune system in some cases and suppress it in others. The finding eventually could lead to new drugs to regulate the immune system by, for example, revving it up to attack tumor cells or tamping it down to prevent the rejection of transplanted organs...
15.04.2012 10:00
Researchers at Boston University School of Medicine (BUSM) have identified a gene that plays a key role in regulating inflammatory response and homeostasis. These findings could help lead to the development of innovative methods to reduce the inflammation associated with cancer, type 2 diabetes and other diseases...
13.04.2012 21:00
A study by Swedish researchers published Online First in The Lancet Oncology suggests that people with Huntington's disease or other diseases known as polyglutamine (polyQ) diseases have a lower risk of developing cancer, due to a common genetic mechanism...
13.04.2012 11:00
In a paper published in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases "en masse", enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies...
Researchers at the University of California, Davis have discovered a key tool that helps sperm and eggs develop exactly 23 chromosomes each. The work, which could lead to insights into fertility, spontaneous miscarriages, cancer and developmental disorders, is published April 13 in the journal Cell. Healthy humans have 46 chromosomes, 23 from the sperm and 23 from the egg...
13.04.2012 10:00
Childhood cancer survivors are living longer and there is an urgent need for better, more comprehensive ways to evaluate their health-related quality of life and need for psychosocial services, according to a review article in Journal of Adolescent and Young Adult Oncology (JAYAO), a multidisciplinary peer-reviewed publication from Mary Ann Liebert, Inc...
13.04.2012 00:00
Patients with Huntington's disease have a considerably lower risk of developing cancer, researchers from Lund University, and Skåne University Hospital, Malmö, Sweden, reported in the journal Lancet Oncology. The same applies to other polyQ (polyglutamine) diseases, the authors added...
12.04.2012 22:00
The Ohio State University uses two different approaches to visualize circulating tumor cells (CTCs) and other unusual circulating cells, with both epithelial and hematopoietic characteristics in metastatic breast cancer (mBC) for their new research...
12.04.2012 18:00
The average American cancer patients lives about two years longer than their opposite number in Europe, says a news report issued by Health Affairs. The authors explain that the higher US costs in cancer therapies appear to have paid off, compared to medical treatments and cancer survival outcomes in Europe...
12.04.2012 11:00
A majority of Michigan oncology practices participating in a statewide consortium followed treatment guidelines for common cancers, but had gaps in managing symptoms and end-of-life care, according to a new study...
12.04.2012 10:00
People who received frequent dental x-rays in the past have an increased risk of developing the most commonly diagnosed primary brain tumor in the United States. That is the finding of a study published early online in Cancer, a peer-reviewed journal of the American Cancer Society...
Cancer is a growing health concern in low- and middle-income countries, and there is an opportunity for Canada to make a significant contribution to help tackle the disease, states an analysis in CMAJ (Canadian Medical Association Journal). Cancer kills more people than HIV/AIDS, tuberculosis and malaria combined...
11.04.2012 23:00
Genetic mutations in cancer cells can lead to treatment resistance, which could result in relapse, yet according to a new study in the journal PLoS Biology, it is possible that the reverse could also happen...
11.04.2012 12:00
A new report by American Cancer Society scientists says new data showing aspirin's potential role in reducing the risk of cancer death bring us considerably closer to the time when cancer prevention can be included in clinical guidelines for the use of aspirin in preventative care...
11.04.2012 11:00
Combining two strategies designed to improve the results of cancer treatment - antiangiogenesis drugs and nanomedicines - may only be successful if the smallest nanomedicines are used...
Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments. Cells without functional lamellipodia are still highly motile but lose their ability to stay on track, report researchers at the Stowers Institute for Medical Research in the online issue of the Journal of Cell Biology...
Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) are developing new methods to inject drugs and genetic payloads directly into cancer cells...
A new analysis provides a closer look at how much cancer patients value hope - with important implications for how insurers value treatment, particularly in end-of-life care...
A team of researchers at Massachusetts Institute of Technology (MIT) in the US has designed nanoparticles that produce proteins when utraviolet (UV) light shines on them: they suggest the idea could be used to create "nano-factories" that make protein-based drugs at tumor sites to fight cancer...
11.04.2012 10:00
An international team of scientists, led by researchers from the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore and National Cancer Centre of Singapore, has identified hundreds of novel genes that are mutated in stomach cancer, the second-most lethal cancer worldwide...
Both radiation and many forms of chemotherapy try to kill tumors by causing oxidative stress in cancer cells. New research from USC on a protein that protects cancer and other cells from these stresses could one day help doctors to break down cancer cells' defenses, making them more susceptible to treatment. In the Journal of Biological Chemistry, scientists led by USC Professor Kelvin J. A...
10.04.2012 12:00
ONCOLOGY Harnessing the power of angiogenesis inhibitors The development of new blood vessels, known as angiogenesis, is critical for processes such as wound healing, but is exploited by tumors to enable more robust growth...
10.04.2012 11:00
People who are diagnosed with cancer have a markedly increased risk of suicide and cardiovascular death during the period immediately after being given the diagnosis. This has been shown in a new study from Karolinska Institutet, published in the prestigious scientific journal the New England Journal of Medicine...
Nanotechnology offers powerful new possibilities for targeted cancer therapies, but the design challenges are many. Northwestern University scientists now are the first to develop a simple but specialized nanoparticle that can deliver a drug directly to a cancer cell's nucleus -- an important feature for effective treatment...
10.04.2012 10:00
The largest study of its kind finds that a history of frequent dental x-rays, particularly at a young age, is tied to an increased risk of developing meningioma, the most common type of primary brain tumor in the United States...
09.04.2012 20:00
A study published online in Environmental Health Perspectives reports that researchers from the National Institutes of Health have discovered how normal stem cells can turn into cancer stem cells and spur tumor growth through exposure to arsenic. Evidence of earlier studies shows that the drinking water of millions of people worldwide is affected by inorganic arsenic, which is a human carcinogen...
09.04.2012 10:00
Researchers at the National Institutes of Health have discovered how exposure to arsenic can turn normal stem cells into cancer stem cells and spur tumor growth. Inorganic arsenic, which affects the drinking water of millions of people worldwide, has been previously shown to be a human carcinogen. A growing body of evidence suggests that cancer is a stem-cell based disease...
Physician-scientists from University Hospitals (UH) Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine presented new research findings in 24 presentations at the Annual Meeting of the American Association for Cancer Research (AACR) in Chicago, Illinois...
08.04.2012 11:00
Scientists at Northwestern University in the US have developed a simple, specialized, star-shaped gold nanoparticle that can deliver drugs directly to the nucleus of a cancer cell. They write about their work in a paper published recently in the journal ACS Nano. Senior author Dr Teri W...
08.04.2012 10:00
A team of scientists, engineers and physicians from Brigham and Women's Hospital (BWH), Dana-Farber Cancer Institute (DFCI), Harvard Medical School (HMS), Massachusetts Institute of Technology (MIT), BIND Biosciences, Translational Genomics Research Institute (TGen), Wayne State University Karmanos Cancer Institute, and Weill Cornell Medical College have found promising effects...
07.04.2012 10:00
A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published in Clinical Cancer Research...
06.04.2012 10:00
A current study shows that the risk for coronary heart disease and stroke increases by almost thirty per cent in a person whose partner has cancer. The cause is probably the negative stress to which the cancer patient's relative is exposed. We know that the relatives of chronically ill patients, especially cancer patients, have an increased risk of mental illness and depression...
Deaths from womb cancer (cancer of the uterus) in the UK have gone up by nearly 20% in the last ten years. The trend follows a steep rise in the number of women diagnosed with cancer of the uterus, and is accompanied by improvements in survival rates, according to new figures from Cancer Research UK released on Thursday...
05.04.2012 23:00
A study published in the April 4 issue of JAMA reveals that patients who receive the drug cetuximab in addition to chemotherapy after undergoing surgery for stage III colon cancer do not have improved disease-free survival. According to the researchers, the chance of cure among patients who undergo surgery for removal of stage III colon cancer is 50%...
05.04.2012 11:00
The drug known as rapamycin is widely used by cancer and transplant patients, and there are hints that it might even help us put off old age and live longer. But, it also comes with a downside: rapamycin leads to diabetes in as many as 15 percent of the people who take it. Now, researchers reporting in the April Cell Metabolism, a Cell Press publication, have figured out why that is...
Oesophageal cancer is a very serious form of cancer that, if not fatal, requires extensive surgery. A new study from Karolinska Institutet shows that when serious complications arise after surgery for oesophageal cancer, many patients suffer other health problems, such as breathlessness, fatigue, insomnia and eating problems, for five years afterwards...
If current trends continue, the cost of having one's genome analyzed will be comparable to that of the weekly supermarket bill. But will this give us the ability to predict which common diseases are likely to afflict us in the future? Well, according to a new study of twins that was published this week in Science Translational Medicine, the answer in most cases is likely to be no...
05.04.2012 10:00
Although cancer recurrence may be the overriding fear for many survivors, nearly half of survivors from a recently presented study died from other conditions. These results indicate survivors could potentially benefit from a more comprehensive, less cancer-focused approach to their health, according to lead researcher Yi Ning, M.D., Sc.D...
Many children with the bone cancer, osteosarcoma, die after the tumor spreads to their lungs. In a critical step toward finding a way to stop metastasis, researchers at Georgetown Lombardi Comprehensive Cancer Center say they have discovered an agent that prevents this type of cancer from spreading to the lungs in mice with the disease...
Hepatitis B-infected patients with significantly longer telomeres - the caps on the end of chromosomes that protect our genetic data - were found to have an increased risk of getting liver cancer compared to those with shorter ones, according to findings presented by researchers at Jefferson's Kimmel Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2012...
The US Food and Drug Administration (FDA) is warning doctors and other health care professionals that fake cancer drug, injectable Altuzan (bevacizumab), has entered the country. Bevacizumab is approved in the USA as Avastin, and sold by Genentech. Injectable Altuzan (400 mg/16 ml) is approved in Turkey, but not the United States, the FDA informs. The fake product has no active ingredient...
04.04.2012 17:00
Genetic mutations in cancer cells can lead to resistance to treatment, thereby potentially resulting in relapse. However, a new article, published in the magazine section of the online, open-access journal PLoS Biology, suggests that the converse may also happen...
04.04.2012 11:00
The chemical (S)-N'-nitrosonornicotine, or (S)-NNN, which is present in smokeless tobacco products, is a strong oral carcinogen, according to results presented at the AACR Annual Meeting 2012, being held March 31 - April 4...
04.04.2012 10:00
Researchers at Fox Chase Cancer Center in Philadelphia have found that a protein associated with other cancers appears to also be important in head and neck cancer, and may consequently serve as a good target for new treatments. The findings were reported at the AACR Annual Meeting...
Scientists at Fox Chase Cancer Center have uncovered more details about how defects in components of the machinery that makes new proteins can lead to blood and other cancers. The findings, which were presented at the AACR Annual Meeting 2012, may one day lead to new targeted therapies that address those problems...
Scientists may have discovered a new paradigm for immunotherapy against cancer by priming antibodies and T cells with cancer stem cells, according to a study published in Cancer Research, a journal of the American Association for Cancer Research...
Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave the primary tumor is in the lymph nodes...
A popular diabetes drug, metformin, appears to help patients with several types of cancer, including cancer of the prostate, liver and pancreas, researchers are revealing or are about to reveal at the American Association For Cancer Research Meeting, 2012, Chicago, USA...
04.04.2012 02:00
According to a study in bmj.com, the risk of developing cancer within the first seven years after receiving a metal-on-metal hip replacement is no higher than in the general population, although further long-term studies are required...
03.04.2012 15:00
Preliminary data from a trial published in Clinical Cancer Research shows that a harmless human virus that occurs naturally could potentially boost the effects of two standard chemotherapy drugs in some cancer patients. Oncolytics Biotech Inc. developed a new drug, RT3D that will be marketed under the trade name of Reolysin. The drug is based on a virus, i.e...
03.04.2012 12:00
One of the major routes of tumor cell dissemination to form metastasis at distant organs in the body is the lymphatic system...
With technological advancements opening the door to less invasive medical procedures, robotic-assisted surgery is becoming increasingly popular, despite being more expensive than traditional surgery. Robotic-assisted surgical removal of the bladder due to cancer is a new approach to the traditional "open" - or more invasive - operation called a radical cystectomy...
03.04.2012 11:00
An early Positron Emission Tomography (PET) response after the initial cycle of neoadjuvant chemotherapy can be used to predict increased survival in patients with soft tissue sarcomas, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center...
03.04.2012 10:00
Metformin, a drug widely used to treat Type II diabetes, may help to prevent primary liver cancer, researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center report in the April 2012 issue of Cancer Prevention Research...
A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2012...
The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. The results also revealed that increases in interleukin-8 levels early after treatment with pazopanib may predict a lack of tumor response to the therapy...
Scientists at Washington University School of Medicine in St. Louis are using powerful DNA sequencing technology not only to identify mutations at the root of a patient's tumor - considered key to personalizing cancer treatment - but to map the genetic evolution of disease and monitor response to treatment...
02.04.2012 10:00
Angiogenesis, the growth of new blood vessels, is a complex process during which different signalling proteins interact with each other in a highly coordinated fashion. The growth factor VEGF and the Notch signalling pathway both play important roles in this process...
01.04.2012 10:00
Research led by Lauren Cole, a public health graduate student, and Dr. Edward Peters, Associate Professor of Public Health and Director of the Epidemiology Program at LSU Health Sciences Center New Orleans, reports that the incidence of head and neck cancer has risen at sites associated with Human Papilloma Virus (HPV) infection, with the greatest increase among middle-aged white men...
A proposed study could help determine if there is a link between living near nuclear power plants or other nuclear facilities and having a higher risk of cancer, but challenges and limitations exist, says a new report from the National Research Council, the operating arm of the National Academy of Sciences and National Academy of Engineering...
31.03.2012 10:00
Patients with papillary renal cell carcinoma, the second most common kidney cancer subtype, face a low risk of tumour recurrence and cancer-related death after surgery. Those are the key findings of a multi-centre study of nearly 600 patients published in the April issue of the urology journal BJUI...
30.03.2012 12:00
Bringing the goal of personalized medicine a step closer, scientists who design anti-cancer treatments and clinical trials now have access to a huge cancer knowledge resource, thanks to a collaboration between industry and academia...
30.03.2012 10:00
A chromosomal abnormality in children with a deadly form of brain cancer is linked with a poorer chance of survival, clinician scientists at The University of Nottingham have discovered...
Researchers at Moffitt Cancer Center in Tampa, Fla., have found - contrary to previous studies linking inferior outcomes in patients with gastrointestinal malignancies to higher body mass index (BMI) - that in their study of BMI and negative outcomes, there was no such link. They concluded that BMI was not associated with either surgical complications or esophageal cancer patient survival...
Treatments for childhood cancers are increasingly successful with cure rates approaching 80%, but success often comes with a downside for the surviving men: the cancer treatments they received as boys can leave them sterile as adults...
More than half of all cancer is preventable, and society has the knowledge to act on this information today, according to Washington University public health researchers at the Siteman Cancer Center in St. Louis...
The goal of cancer treatment is to match the right drug to the right target in the right patient. But before such "personalized" drugs can be developed, more knowledge is needed about specific genomic alterations in cancers and their sensitivity to potential therapeutic agents...
New cancer rates among men fell 0.6% annually from 1994 to 2008, among women they dropped 0.5% yearly from 1998 to 2006, and among children rose from 1992 to 2008, according to the Annual Report to the Nation on the Status of Cancer, which was published in the journal Cancer. From 2004 to 2008, average cancer death rates for both sexes dropped by 1.6% annually...
29.03.2012 22:00
Profiling genetic alterations in cancer with drug sensitivity is a way to develop a tailored approach to treating patients with cancer, researchers from Europe and the USA reported in the journal Nature. In what they describe as the "largest study of its kind", hundreds of associations between cancer gene mutations and anticancer medication sensitivity or resistance have been uncovered...
29.03.2012 20:00
Results of a phase II trial reveal that ipilimumab, a drug belonging to a new class of immune-based therapies which alter the way the immune system fights cancer, may help shrink some tumors and may slow progression of secondary tumors in the brain (metastases) in some patients with advanced melanoma. The study is published Online First in The Lancet Oncology...
According to a study published Online First by The Lancet, breast, cervical and stomach cancers are responsible for the majority of cancer deaths among women in India, while lung, oral and stomach cancers are the leading causes of cancer death in Indian men. The study was conducted by Professor Prabhat Jha, Center for Global Health Research, St...
29.03.2012 14:00
In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 March 2012. The team uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs...
29.03.2012 13:00
Researchers from Emory and the Georgia Institute of Technology have designed a new treatment approach that appears to halt the spread of cancer cells into normal brain tissue in animal models. Treating invasive brain tumors with a combination of chemotherapy and radiation has improved clinical outcomes, but few patients survive longer than two years after diagnosis...
29.03.2012 11:00
Just as the familiar sugar in food can be bad for the teeth and waistline, another sugar has been implicated as a health menace and blocking its action may have benefits that include improving long-term memory in older people and treating cancer...
A study led by Dr Janet Shipley from The Institute of Cancer Research (ICR) in London in collaboration with Dr Mauro Delorenzi from the SIB Swiss Institute of Bioinformatics in Lausanne has shown that a simple genetic test could help predict the aggressiveness of rhabdomyosarcoma tumours in children...
28.03.2012 12:00
A single antibody caused tumors from seven different human cancers transplanted into mice to shrink or disappear, according to a new study led by Stanford University School of Medicine in the US. The researchers hope to repeat this dramatic finding with tests in humans within the next two years...
The theory of quantum metabolism is the idea that quantum processes, such as entanglement, influence the metabolism of cells. This idea offers scientists a new explanation for the metabolic changes that cause healthy cells to transform into cancerous ones. The metamorphosis gives cancerous cells the ability to outcompete healthy cells for space and nutrients, causing the disease to spread...
In search of a different perspective on the physics of cancer, Princeton University and University of California, San Francisco researchers teamed up to use game theory to look for simplicity within the complexity of the dynamics of cooperator and cheater cells under metabolic stress conditions and high spatial heterogeneity...
Researchers have developed multiple techniques and procedures to detect cancer cells during the earliest stages of the disease or after treatment. But one of the major limitations of these technologies is their inability to detect the presence of only a few cancer cells...
Cancer remains a medical mystery - despite all of the research efforts devoted to understanding and controlling it. The most sought-after tumor model is one that would be able to formulate theoretical and computational tools to predict cancer progression and propose individual treatment strategies...
Using nanoparticles and alternating magnetic fields, University of Georgia scientists have found that head and neck cancerous tumor cells in mice can be killed in half an hour without harming healthy cells...
28.03.2012 11:00
Advances in chemotherapy have dramatically improved the outlook for many cancer patients, but the side effects of this treatment are daunting. A new generation of chemotherapy drugs with fewer side effects is the goal of Edward J. Merino, assistant professor of chemistry at the University of Cincinnati...
Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close more routes and develop better drugs. Kinase enzymes deliver phosphates to cell proteins in a process called phosphorylation, switching a cellular function on or off...
28.03.2012 10:00
Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody, according to a new study from the Stanford University School of Medicine. The antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system...
The under-reporting of the possible side effects of heart damage from cancer drugs puts patients at an increased risk for heart failure, according to two researchers at the Stanford University School of Medicine...
An international team of scientists has announced a new advance in the ability to target and destroy certain cancer cells. A group led by the University of Leicester has shown that particular cancer cells are especially sensitive to a protein called p21...
A new study from the US finds few young women being treated for cancer take steps to preserve their fertility, for instance so they can start a family later. Dr Mitchell Rosen, of the University of California, San Francisco (UCSF), and colleagues, also found disparities among different groups of young women, with some more likely to take steps to freeze eggs or embryos than others...
27.03.2012 20:00
US researchers suggest there is an underlying mechanism that affects both cancer and low LDL (so-called "bad") cholesterol, because they found low LDL cholesterol in people with no history of taking drugs to lower their cholesterol precedes cancer risk by decades...
27.03.2012 16:00
According to a new study from the University of Leicester that has been published in the international journal Sociology of Health and Illness, patient information leaflets for cancer trials miss the mark, with patients declaring they are far too long, incomprehensible, and even intimidating...
A study published in The Journal of Biological Chemistry reveals that certain cancer cells are particularly sensitive to p21, a protein that typically forces normal and cancer cells to stop dividing, which recently displayed its ability to kill cancer cells in some cases...
27.03.2012 13:00
With more than 15 million endoscope procedures done on patients each year in the U.S. alone, scientists reported evidence that a new version of these flexible instruments for diagnosing and treating disease shows promise for helping surgeons more completely remove cancerous tumors...
27.03.2012 10:00
At the heart of the immune system that protects our bodies from disease and foreign invaders is a vast and complex communications network involving millions of cells, sending and receiving chemical signals that can mean life or death. At the heart of this vast cellular signaling network are interactions between billions of proteins and other biomolecules...
Shortly after a mouse embryo starts to form, some of its stem cells undergo a dramatic metabolic shift to enter the next stage of development, Seattle researchers report. These stem cells start using and producing energy like cancer cells. This discovery is published in EMBO, the European Molecular Biology Organization journal...
UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. Published online in Nature Medicine, the team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae...
26.03.2012 11:00
Scientists are enlisting the living, self-propelled microbes found in pond scum - the pea-green surface slicks that form on ponds - in the development of a long-awaited new test to detect the cells that spread cancer through the bloodstream from the original tumor to new sites in the body...
26.03.2012 10:00
New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation...
Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite," a chemical produced by some brain tumors' warped metabolism, via non-invasive imaging. Their approach could allow doctors to know not only that a brain tumor is there, but also that it carries a particular genetic mutation...
A study published by University of Kentucky researchers shows that survivors of multiple cancers report unhealthier behaviors post-diagnosis than control counterparts. Published in the Annals of Behavioral Medicine, the study recorded answers regarding health status and health behaviors from 404,525 adults using the Behavioral Risk Factor Surveillance System survey...
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