Regulation of leukocyte function by adenosine receptors.
29.05.2011, 23:00
Authors: Linden J The immune system responds to cues in the microenvironment to make acute and chronic adaptations in response …
Scoring System May Predict Chemo Response in Ovarian Cancer Patients
14.04.2012, 05:30
A study published today details a scoring system that may predict which ovarian cancer patients responded to first-line platinu…
Enlisting The Immune System To Guide Chemotherapy For Breast Cancer
03.04.2011, 14:00
A study published in Cancer Discovery, the newest journal of the American Association for Cancer Research, debuting here at the…
Potential Key To Immune Suppression In Cancer Revealed By Study
23.01.2012, 09:00
In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla., and the University o…
Protein Unmasks Pathogenic Fungi To Activate Immune Response
10.08.2011, 09:00
The first step in defending against a hostile attack is identifying the enemy. It's how a healthy immune system mounts a respon…
Validation of the Supportive Care Needs Survey—short form 34 with a simplified response format in …
30.07.2011, 17:35
ConclusionsThe SCNS†SF34 with revised response format maintained the same factor structure as the original, with five domains…
A New In Vivo Model System to Assess the Toxicity of Semiconductor Nanocrystals
05.05.2011, 16:35
In the emerging area of nanotechnology, a key issue is related to the potential impacts of the novel nanomaterials on the envir…
Global Identification of Androgen Response Elements
28.08.2011, 03:40
Chromatin immunoprecipitation (ChIP) is an invaluable tool in the study of transcriptional regulation. ChIP methods require bot…
A trio of microRNAs that control Toll-like receptor signalling
27.06.2011, 01:00
Toll-like receptors (TLRs) in the host recognize conserved microbial products and defend against pathogenic attack by initiatin…
Functional Foods and Herbs as Potential Immunoadjuvants and Medicines in Maintaining Healthy Immune …
19.11.2010, 01:18
Herbs and traditional foods have been demonstrated for their effectiveness on lifestyle-related diseases like diabetes, heart d…
A Hybrid Approach for the Random Dynamics of Uncertain Systems under Stochastic Loading
05.05.2011, 16:35
This paper presents a hybrid Galerkin/perturbation approach based on Radial Basis Functions for the dynamic analysis of mechani…
Chromosomal copy number alterations are associated with tumor response to chemoradiation in locally …
18.05.2011, 16:50
AbstractRectal cancer response to chemoradiation (CRT) varies from no response to a pathologic complete response (pCR). Identif…
Immune system may guide chemotherapy
03.04.2011, 17:40
ORLANDO, Fla. � A study published in Cancer Discovery, the newest journal of the American Association for Cancer Research, de…
GeparTrio: Adapting Neoadjuvant Chemotherapy Based on Interim Response Improved DFS and OS Outcomes
09.12.2011, 13:55
Capsule Summary - The response-guided chemotherapy strategies evaluated in this study, namely treatment intensification for pat…
Detection of MYCN DNA in the cerebrospinal fluid for diagnosing isolated central nervous system rela…
16.01.2011, 01:00
We present the case of a 1†year†old female with stage†4 neuroblastoma with MYCN amplification; she was treated with five …
Study points to way of improving chemotherapy response
03.09.2011, 16:16
Blocking key proteins could improve response to a common chemotherapy drug, suggests a new study which used cancer cells grown …
Using genetically engineered mice for radiation research.
30.08.2011, 09:52
Authors: Kirsch DG Abstract The laboratory mouse has been used for many decades as a model system for radiation research. Recen…
Association between the expression pattern of p16, pRb and p53 and the response to intravesical baci…
27.07.2011, 07:14
There is limited data regarding the association between the expression of cell cycle†regulating molecules and the response of…
Radiologists Urge FDA To Accept PET-Based Tumor Response Criteria in Clinical TrialsRadiologists Urg…
27.06.2011, 13:04
The FDA has accepted only CT scans and Response Evaluation Criteria in Solid Tumors/RECIST to date. What clinical impact might …
[Comment] Optimising the lymphoma response criteria in the era of targeted therapy
27.06.2011, 18:48
With hundreds of new compounds being developed for the treatment of cancer, decisions must be urgently made to prioritise the u…
New high-speed 3-D imaging system holds potential for improved cancer screening
01.08.2011, 18:03
Researchers have developed a new imaging system that enables high-speed, three-dimensional (3-D) imaging of microscopic pre-can…
Response Genetics raises $7.8 million in stock sale
03.02.2012, 22:52
Response Genetics Inc. said it has raised more than $7.8 million through the private placement of 5.3 million in newly issued s…
Response Genetics raises $7.8 million in stock sale
03.02.2012, 23:53
Response Genetics Inc. said it has raised more than $7.8 million through the private placement of 5.3 million in newly issued s…
In Response to Dr. Garbow and Colleagues
12.02.2011, 21:54
To the Editor: Thank you for the opportunity to respond to the recent comments of Dr. Garbow and Dr. Ackerman, who both share o…
Boston Scientific's SpyGlass® Direct Visualization System Achieves Global Utilization Milestones
05.05.2011, 09:00
Boston Scientific Corporation (NYSE: BSX) announced several milestones in the adoption of its SpyGlass® Direct Visualization S…
Immune system may guide chemotherapy for breast cancer
03.04.2011, 06:00
(American Association for Cancer Research) A study published in Cancer Discovery, the newest journal of the American Associatio…
Vemurafenib achieves good response in genetic melanoma
13.03.2012, 00:13
Around half of patients with a common type of genetic melanoma respond to the novel drug vemurafenib, with over 80% showing res…
Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin's Ly…
16.07.2011, 01:00
Conclusions, these results suggest that MDR1 C3435T polymorphism might play a role in HL occurrence; however this polymorphism …
Multiengine Speech Processing Using SNR Estimator in Variable Noisy Environments
08.02.2012, 14:24
We introduce a multiengine speech processing system that can detect the location and the type of audio signal in variable noisy…
FDA To Approve Shared System REMS For TIRF Products
03.01.2012, 10:00
The U.S. Food and Drug Administration approved a single shared Risk Evaluation and Mitigation Strategy (REMS) for the transmuco…
Early cytogenetic and molecular response during first†line treatment of chronic myeloid leukemia i…
20.05.2011, 16:21
AbstractChronic myeloid leukemia (CML) depends on the kinase activity of the BCR†ABL1 fusion protein. This dependency has led…
Humoral response to catumaxomab correlates with clinical outcome: Results of the pivotal phase II/II…
23.06.2011, 01:00
In conclusion, HAMA development may be a biomarker for catumaxomab response and patients who developed HAMAs sooner derived gre…
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
21.06.2011, 01:00
Conclusions: Together our results suggest that antigenicity is a local property of the protein sequences and that protein seque…
Outsmarting Cancer Cells: Researchers Learn How They Spread
08.04.2011, 19:00
Saint Louis University researchers have identified a novel mechanism to control the traffic of cells and fluid from tissues to …
Tumor-Specific HMG-Coa Reductase Expression in Primary Premenopausal Breast Cancer Predicts Response…
04.03.2011, 05:00
The predictive value of HMG-CoAR expression is examined in relation to tamoxifen response for patients who have yet to reach me…
Healthy Breast Cells Help Kill Cancer Cells
14.04.2011, 11:00
Healthy epithelial cells in breast tissue secrete an anticancer protein called interleukin 25 (IL25) that instructs malignant c…
Nonoperative Approaches to Rectal Cancer: A Critical Evaluation
07.06.2011, 16:44
A neoadjuvant multimodality approach with chemoradiation therapy (CRT) is the preferred treatment strategy for most distal rect…
New Perspectives On Cancer And The Immune System
26.03.2011, 08:00
In a new review article published in yesterday's special section of Science focusing on the past forty years since the U.S. dec…
Bone Scan Index: A Quantitative Treatment Response Biomarker for Castration-Resistant Metastatic Pro…
09.02.2012, 06:00
Conclusion These data furnish early evidence that on-treatment changes in BSI are a response indicator and support further expl…
Increase in circulating endothelial progenitor cells predicts response in patients with advanced non…
23.02.2012, 06:00
AbstractPrevious reports have demonstrated that circulating endothelial progenitor cells (CEPs) are released in response to cyt…
Genomic Test Shows Promise as Predictor of Chemotherapy Response, Survival for Women With Invasive B…
12.05.2011, 01:00
A new genomic test combining multiple signatures - a patient's estrogen receptor status, endocrine therapy response, chemothera…
AML Mutations Predict Response to High-Dose ChemotherapyAML Mutations Predict Response to High-Dose …
14.03.2012, 22:00
Research finding adds detail to a complex portrait of acute myeloid leukemia (AML). Medscape Medical News (Source: Medscape Hem…
New Australian Drug Shows Positive Response In Patients With Multiple Myeloma Blood Cancer
17.06.2011, 10:00
Australian monoclonal antibody company, Immune System Therapeutics Limited (IST), today announced it would double patient recru…
FDA issues complete response letter for 5-ARI PCa risk reduction indication
08.02.2011, 19:00
GlaxoSmithKline has received a complete response letter from the FDA for the supplemental new drug application for dutasteride …
FDA Approves 3-D Mammography System
11.02.2011, 21:40
The FDA approved the first three-dimensional mammography system developed by Hologic to screen for breast cancer. (Source: WSJ.…
New Study Reveals How The Immune System Responds To Hepatitis "A" Virus
21.06.2011, 09:00
A surprising finding in a study comparing hepatitis C virus (HCV) with hepatitis A virus (HAV) infections in chimpanzees by a t…
Boston Scientific Announces FDA Approval Of Renegade(R) HI-FLOâ„¢ Fathom(R) Pre-Loaded System
01.02.2011, 10:00
Boston Scientific Corporation (NYSE: BSX) announced that the U.S. Food and Drug Administration (FDA) has approved its RenegadeÂ…
Performance characteristics of a novel radioactive isotope detection and notification system designe…
25.04.2011, 19:30
Authors: Oh Kim J, Huq MS, Novotny J, Bednarz G, Palatine R, Reilly M, Izadbakhsh M, Paris P, Greenberger JS Recently, Universi…
23 Patients With Organ Confined Low Risk Prostate Cancer Have Been Treated In Trials Using The ExAbl…
13.07.2011, 14:00
the global leader in MR-guided focused ultrasound technology and the only company to receive FDA approval for its ExAblate® sy…
Autophagy and DNA Damage Response
14.03.2012, 05:00
Histone deacetylase (HDAC) inhibitors are clinically relevant because they are used as anticancer drugs. Recent evidence sheds …
Researchers on the trail of a treatment for cancer of the immune system
19.08.2011, 06:00
(University of Copenhagen) Danish researchers from the University of Copenhagen have become the first in the world to regulate …
In Response to Dr. Williams
06.05.2011, 00:24
To the Editor: We thank Dr. Williams for his comments on our recently published method for estimating radiation dose–response…
South Florida Radiation Oncology On The Forefront Of Cancer Treatment With The TrueBeamâ„¢ Radiother…
06.08.2011, 10:00
In a promising development for cancer patients in The Palm Beach area, South Florida Radiation Oncology announced today that it…
Metastatic breast cancer hitches a free ride from the immune system
09.02.2012, 06:00
(BioMed Central) Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymp…
Potential For Improved Cancer Screening With New High-Speed 3-D Imaging System
02.08.2011, 14:00
Researchers at the Massachusetts Institute of Technology (MIT) have developed a new imaging system that enables high-speed, thr…
Evaluation of prognostic and predictive value of microtubule associated protein tau in two independe…
02.09.2011, 01:00
Conclusions: Quantitative measurement of MAP-tau expression has prognostic value in both cohorts, with high expression associat…
DNA Damage Response and Inflammatory Signaling Limit the MLL-ENL-Induced Leukemogenesis In Vivo
17.04.2012, 02:00
Sylvia Takacova, Robert Slany, Jirina Bartkova, Viktor Stranecky, Petr Dolezel, Pavla Luzna, Jiri Bartek, Vladimir Divoky. Acti…
Siemens MAMMOMAT Inspiration Digital Mammography Commercially Available In U.S.
18.11.2010, 15:00
Siemens announces that the MAMMOMAT® Inspiration Full-Field Digital Mammography System is now commercially available in the Un…
Early Detection of Tumor Response by FLT/MicroPET Imaging in a C26 Murine Colon Carcinoma Solid Tumo…
16.08.2011, 17:06
In this study, we evaluate the early response of colon carcinoma to the chemotherapeutic drug, lipo-Dox, in C26 murine colorect…
FDA Approves First 3-D Mammography Imaging System
12.02.2011, 21:30
Breast imaging has gone 3-D. The FDA announced today the approval of Hologic Inc.’s Selenia Dimensions System, the first X-ra…
Gentiana asclepiadea and Armoracia rusticana can modulate the adaptive response induced by zeocin in…
25.11.2011, 13:25
Authors: Hudecova A, Hasplova K, Kellovska L, Ikreniova M, Miadokova E, Galova E, Horvathova E, Vaculcikova D, Gregan F, Dusins…
[Comment] Retraction—validation of gene signatures that predict the response of breast cancer to n…
29.01.2011, 15:19
The Lancet Oncology and the European co-authors of the article mentioned above, recently expressed concern over the validity of…
Genomic Test Shows Promise As Predictor Of Chemotherapy Response, Survival For Women With Invasive B…
11.05.2011, 09:00
A new genomic test combining multiple signatures a patient's estrogen receptor status, endocrine therapy response, chemotherapy…
HLA class II genotype can help to predict response to therapy
23.03.2011, 14:41
A number of new agents have been approved for systemic therapy of metastatic renal cell carcinoma (mRCC) recently. Thereby, pro…
Antinociceptive efficacy of verticinone in murine models of inflammatory pain and Paclitaxel induced…
06.09.2011, 19:16
Authors: Xu F, Xu S, Wang L, Chen C, Zhou X, Lu Y, Zhang H Abstract Verticinone, an isosteroidal alkaloid separated from Bulbus…
Scoring System May Tell the Dying How Long They Have to Live
26.08.2011, 09:00
Title: Scoring System May Tell the Dying How Long They Have to LiveCategory: Health NewsCreated: 8/25/2011 8:06:00 PMLast Edito…
Serum DNA methylation for monitoring response to neoadjuvant chemotherapy in breast cancer patients
12.03.2012, 05:00
AbstractPatients with large or non‐operable breast cancers often receive neoadjuvant chemotherapy to facilitate full resection …
Prognostic factors of a good response to initial therapy in children and adolescents with differenti…
08.04.2011, 19:59
BACKGROUND: Therapeutic approaches in pediatric populations are based on adult data because there is a lack of appropriate data…
Inotuzumab Ozogamicin Achieves ‘Markedly Long’ Antitumor Response in Indolent B-Cell NHL
06.04.2012, 18:30
Inotuzumab ozogamicin has achieved a markedly long antitumor response in patients with refractory or relapsed indolent B-cell n…
I-131 Dose Response for Incident Thyroid Cancers in Ukraine Related to the Chornobyl AccidentI-131 D…
26.07.2011, 13:04
This article explains. Environmental Health Perspectives (Source: Medscape Today Headlines)
Response shift in the assessment of anxiety, depression and perceived health in urologic cancer pati…
29.04.2011, 17:58
HINZ A., FINCK BARBOZA C., ZENGER M., SINGER S., SCHWALENBERG T. & STOLZENBURG J.†U. (2011) European Journal of Cancer Care 
Identifying Cancer Cells For Immune System Attack With DNA Sequencing
10.02.2012, 09:00
DNA sequences from tumor cells can be used to direct the immune system to attack cancer, according to scientists at Washington …
Antiviral Effects of Extracellular CCN1
14.03.2012, 05:00
In this study, we examined a hypothesized role for CCN1 in limiting the efficacy of oncolytic viral therapy for glioma, based o…
The biological correlates of macroscopic breast tumour structure measured using fractal analysis in …
23.03.2012, 18:44
In this study, we measured the structural characteristics of 33 breast tumours in patients who were to receive neoadjuvant chem…
Functional Interaction between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcript…
16.01.2012, 06:00
Within solid tumor microenvironments, lactic acidosis, and hypoxia each have powerful effects on cancer pathophysiology. Howeve…
Cleveland Area Brain Cancer Patients Now Testing Revolutionary Personalized Immune Therapy For Cance…
22.07.2011, 19:00
A ground-breaking new treatment in late-stage clinical trials is giving Cleveland area patients new hope in their battle agains…
T-Cell Ability To Target Cancer Restored By Arginine
26.11.2011, 09:00
In many cases, tumors suppress a patient's immune system in a way that keeps the cancer safe from immune system attack. This is…
Interleukin-8 expression associated with canine mammary tumors.
29.08.2011, 15:48
Authors: Zuccari DA, Castro R, Gelaleti GB, Mancini UM Abstract The use of prognostic markers for mammary cancer is important f…
Volumetric response evaluation after intensity modulated radiotherapy in patients with supratentoria…
24.12.2011, 17:49
Authors: Cho KH, Choi JH, Kim JY, Lee SH, Yoo H, Shin KH, Kim TH, Moon SH, Lee SH, Park HC Abstract Radiotherapy is frequently …
Developing cancer immunotherapies
24.03.2011, 16:15
AbstractEffective antitumor responses require communication between antigen†presenting cells, T†cell subsets, B cells and n…
Analysis of Treg Cell Population Alterations in the Peripheral Blood of Patients Treated Surgically …
30.05.2011, 15:52
Conclusion  It would seem that the alteration in the Treg cell subpopulation could be a key factor in determining the status …
Global Attractivity and Periodic Solution of a Discrete Multispecies Cooperation and Competition Pre…
04.08.2011, 16:05
We propose a discrete multispecies cooperation and competition predator-prey systems. For general nonautonomous case, sufficien…
B lymphocytes as effector cells in the immunotherapy of cancer
06.09.2011, 01:00
AbstractOver the years, the role of B cells in the host immune response to malignancy has been overshadowed by our focus on T c…
Immune System Could Help Fight Lung Cancer
05.05.2011, 07:00
(Ivanhoe Newswire)-- Scientists at UCLA may have added a new weapon to the arsenal in the fight against lung cancer: the human …
Understanding in vivo blood cell migration-Drosophila hemocytes lead the way.
20.12.2010, 03:20
Authors: Evans IR, Wood W Drosophila embryonic hemocytes have emerged as a potent system to analyze the roles of key regulators…
From tumor immunology to cancer immunotherapy: Miles to go
24.02.2011, 01:00
Manjul TiwariJournal of Cancer Research and Therapeutics 2010 6(4):427-431Advances in tumor immunology are supporting the clini…
On the Dynamics of the Furuta Pendulum
13.04.2011, 16:53
The Furuta pendulum, or rotational inverted pendulum, is a system found in many control labs. It provides a compact yet impress…
Clinical relevance of thiopurine S-methyltransferase gene polymorphisms.
30.04.2011, 06:45
Authors: Mladosievicova B, Dzurenkova A, Sufliarska S, Carter A The therapeutic response to thiopurines may result in either se…
A loose grip provides better chemotherapy
05.02.2011, 23:00
Researchers have found that cancer patients may get a bigger bang and fewer side effects with a new take on a drug delivery sys…
A New Method for Synthesizing Radiation Dose–Response Data From Multiple Trials Applied to Prostat…
06.05.2011, 00:24
To the Editor: The authors are to be commended for bringing meta-analytical methods to the field of radiation dose–response m…
Multimodality Animal Rotation Imaging System (MARS) for In Vivo Detection of Intraperitoneal Tumors
29.09.2011, 00:42
Conclusion  We describe the use of near†infrared nanoparticle probes for in vivo imaging of metastatic ovarian cancer model…
[Review] Treatment implications of the emerging molecular classification system for melanoma
27.08.2011, 15:06
SummaryMelanoma is an aggressive disease with few standard treatment options. The conventional classification system for this d…
Computerized Classification of Intraductal Breast Lesions Using Histopathological Images
26.06.2011, 21:54
In this study, a prototype system for automatically classifying breast microscopic tissues to distinguish between UDH and actio…